SCHEDULE 13G/A

C4 Therapeutics Inc

Common Stock, par value $0.0001 per share · CUSIP: 12529R107

Event date: 2025-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Soleus Private Equity Fund III, L.P.

  Shares: 6,072,822.00 · Class: 5.9%

• Soleus Private Equity GP III, LLC

  Shares: 6,072,822.00 · Class: 5.9%

• Soleus PE GP III, LLC

  Shares: 6,072,822.00 · Class: 5.9%

• Soleus Capital Master Fund, L.P.

  Shares: 10,361,860.00 · Class: 9.99%

• Soleus Capital, LLC

  Shares: 10,361,860.00 · Class: 9.99%

• Soleus Capital Group, LLC

  Shares: 10,361,860.00 · Class: 9.99%

• Soleus Capital Management, L.P.

  Shares: 10,334,114.00 · Class: 9.99%

• Soleus GP, LLC

  Shares: 10,334,114.00 · Class: 9.99%

• Guy Levy

  Shares: 10,334,114.00 · Class: 9.99%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.