SCHEDULE 13G

TALPHERA INC COM NEW

Common Stock, $0.001 par value · CUSIP: 00444T209

Event date: 2025-09-10

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Rock Springs Capital Management LP

  Shares: 3,589,186.00 · Class: 7.88%

• Rock Springs Capital LLC

  Shares: 3,589,186.00 · Class: 7.88%

• Rock Springs Capital Master Fund LP

  Shares: 2,841,954.00 · Class: 6.24%

• Mark Bussard

  Shares: 3,589,186.00 · Class: 7.88%

• Kris Jenner

  Shares: 3,589,186.00 · Class: 7.88%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.