SCHEDULE 13G/A

Xencor Inc

Common Stock, par value $0.01 per share · CUSIP: 98401F105

Event date: 2025-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• BIOTECHNOLOGY VALUE FUND L P

  Shares: 3,798,627.00 · Class: 5.3%

• BVF I GP LLC

  Shares: 3,798,627.00 · Class: 5.3%

• BIOTECHNOLOGY VALUE FUND II LP

  Shares: 2,787,735.00 · Class: 3.9%

• BVF II GP LLC

  Shares: 2,787,735.00 · Class: 3.9%

• Biotechnology Value Trading Fund OS LP

  Shares: 439,372.00 · Class: 0.6%

• BVF Partners OS Ltd.

  Shares: 439,372.00 · Class: 0.6%

• BVF GP HOLDINGS LLC

  Shares: 6,586,362.00 · Class: 9.2%

• BVF PARTNERS L P/IL

  Shares: 7,133,720.00 · Class: 9.99%

• BVF INC/IL

  Shares: 7,133,720.00 · Class: 9.99%

• LAMPERT MARK N

  Shares: 7,133,720.00 · Class: 9.99%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.