SCHEDULE 13G/A

MEREO BIOPHARMA GROUP PLC

Ordinary Shares, nominal value EURO0.003 per share, represented by American Depository Shares · CUSIP: 589492107

Event date: 2025-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Frazier Life Sciences Public Fund, L.P.

  Shares: 0.00 · Class: 0.0%

• FHMLSP, L.P.

  Shares: 0.00 · Class: 0.0%

• FHMLSP, L.L.C.

  Shares: 0.00 · Class: 0.0%

• Frazier Life Sciences X, L.P.

  Shares: 0.00 · Class: 0.0%

• FHMLS X, L.P.

  Shares: 0.00 · Class: 0.0%

• FHMLS X, L.L.C.

  Shares: 0.00 · Class: 0.0%

• Frazier Life Sciences XI, L.P.

  Shares: 0.00 · Class: 0.0%

• FHMLS XI, L.P.

  Shares: 0.00 · Class: 0.0%

• FHMLS XI, L.L.C.

  Shares: 0.00 · Class: 0.0%

• James N. Topper

  Shares: 0.00 · Class: 0.0%

• Patrick J. Heron

  Shares: 0.00 · Class: 0.0%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.