SCHEDULE 13G

REGULUS THERAPEUTICS INC

Common Stock, par value $0.001 per share · CUSIP: 75915K309

Event date: 2025-04-01

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Point72 Asset Management, L.P.

  Shares: 3,923,806.00 · Class: 5.9%

• Point72 Capital Advisors, Inc.

  Shares: 3,923,806.00 · Class: 5.9%

• Steven A. Cohen

  Shares: 3,923,806.00 · Class: 5.9%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.