SCHEDULE 13G/A

INSMED INC

Common stock, par value $0.01 per share · CUSIP: 457669307

Event date: 2024-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Darwin Global Management, Ltd.

  Shares: 12,960,538.00 · Class: 7.2%

• Dr. Abhishek Trehan

  Shares: 12,960,538.00 · Class: 7.2%

• Darwin Global Master Fund, Ltd.

  Shares: 11,480,655.00 · Class: 6.4%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.