SCHEDULE 13G/A

Stoke Therapeutics Inc

Common Stock, par value $0.0001 per share · CUSIP: 86150R107

Event date: 2025-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Baker Bros. Advisors LP

  Shares: 3,336,697.00 · Class: 5.8%

• Baker Bros. Advisors (GP) LLC

  Shares: 3,336,697.00 · Class: 5.8%

• Julian C. Baker

  Shares: 3,336,697.00 · Class: 5.8%

• Felix J. Baker

  Shares: 3,336,697.00 · Class: 5.8%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.