SCHEDULE 13D/A

SKYE BIOSCIENCE INC

Common Stock, par value $0.001 · CUSIP: 83086J200

Event date: 2024-12-17

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• 5AM Partners VII, LLCReported CIK 0001873545

  Shares: 9,872,599.00 · Class: 30.8%

• 5AM Ventures VII, L.P.Reported CIK 0001844435

  Shares: 9,872,599.00 · Class: 30.8%

• 5AM Partners II, LLCReported CIK 0001555952

  Shares: 1,745,962.00 · Class: 5.8%

• 5AM Ventures II, L.P.Reported CIK 0001386509

  Shares: 1,679,685.00 · Class: 5.5%

• 5AM Co-Investors II, L.P.Reported CIK 0001390376

  Shares: 66,277.00 · Class: 0.2%

• Andrew J. SchwabReported CIK 0001598549

  Shares: 11,696,895.00 · Class: 36.4%

• Kush ParmarReported CIK 0001664281

  Shares: 9,872,599.00 · Class: 30.8%

• John D. DiekmanReported CIK 0001240357

  Shares: 1,745,962.00 · Class: 5.8%

• Scott M. RocklageReported CIK 0001219014

  Shares: 1,745,962.00 · Class: 5.8%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.