SCHEDULE 13G/A

Adagene Inc.

Ordinary shares, par value US$0.0001 per share · CUSIP: 005329107

Event date: 2025-03-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• WuXi PharmaTech Healthcare Fund I L.P.

  Shares: 4,978,628.00 · Class: 8.5%

• WuXi AppTec Co., Ltd.

  Shares: 4,978,628.00 · Class: 8.5%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.