SCHEDULE 13G/A

Zymeworks Inc

Common Stock, par value $0.00001 per share · CUSIP: 98985Y108

Event date: 2025-06-30

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Redmile Group, LLC

  Shares: 4,150,627.00 · Class: 5.6%

• Jeremy C. Green

  Shares: 4,150,627.00 · Class: 5.6%

• Redmile Biopharma Investments III, L.P.

  Shares: 3,470,727.00 · Class: 4.6%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.