SCHEDULE 13G/A

APPLIED THERAPEUTICS INC

Common Stock, par value $0.0001 per share · CUSIP: 03828A101

Event date: 2025-12-11

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Alexandria Real Estate Equities, Inc.

  Shares: 6,500,000.00 · Class: 4.3%

• Alexandria Venture Investments, LLC

  Shares: 4,450,000.00 · Class: 3.0%

• Alexandria Equities No. 7, LLC

  Shares: 2,050,000.00 · Class: 1.4%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.