SCHEDULE 13G

Xencor Inc

Common Stock, par value $0.01 per share · CUSIP: 98401F105

Event date: 2025-10-09

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• BIOTECHNOLOGY VALUE FUND L P

  Shares: 2,467,127.00 · Class: 3.5%

• BVF I GP LLC

  Shares: 2,467,127.00 · Class: 3.5%

• BIOTECHNOLOGY VALUE FUND II LP

  Shares: 1,793,209.00 · Class: 2.5%

• BVF II GP LLC

  Shares: 1,793,209.00 · Class: 2.5%

• Biotechnology Value Trading Fund OS LP

  Shares: 286,542.00 · Class: 0.4%

• BVF Partners OS Ltd.

  Shares: 286,542.00 · Class: 0.4%

• BVF GP HOLDINGS LLC

  Shares: 4,260,336.00 · Class: 6.0%

• BVF PARTNERS L P/IL

  Shares: 4,619,341.00 · Class: 6.5%

• BVF INC/IL

  Shares: 4,619,341.00 · Class: 6.5%

• LAMPERT MARK N

  Shares: 4,619,341.00 · Class: 6.5%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.