SCHEDULE 13D/A

Standard BioTools Inc

Common Stock, $0.001 par value per share · CUSIP: 34385P108

Event date: 2025-11-25

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Casdin Capital, LLCReported CIK 0001534261

  Shares: 88,433,856.00 · Class: 22.9%

• Casdin Private Growth Equity Fund II, L.P.Reported CIK 0001891102

  Shares: 13,939,637.00 · Class: 3.6%

• Casdin Private Growth Equity Fund II GP, LLCReported CIK 0001919480

  Shares: 13,939,637.00 · Class: 3.6%

• Casdin Partners Master Fund, L.P.Reported CIK 0001534265

  Shares: 71,750,000.00 · Class: 18.7%

• Casdin Partners GP, LLCReported CIK 0001534260

  Shares: 71,750,000.00 · Class: 18.7%

• Eli CasdinReported CIK 0001534264

  Shares: 93,442,787.00 · Class: 24.2%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.