SCHEDULE 13D/A

CENTESSA PHARMACEUTICALS PLC

Ordinary shares, par value 0.002 GBP per share · CUSIP: 152309100

Event date: 2025-11-25

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• General Atlantic Cooperatief U.A.Reported CIK 0001859266

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic UM B.V.

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic Partners (Bermuda) IV, L.P.

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic Partners (Bermuda) EU, L.P.

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic Partners (Lux) SCSp

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic GenPar (Lux) SCSp

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic (Lux) S.a r.l.

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic GenPar (Bermuda), L.P.

  Shares: 7,366,818.00 · Class: 5.0%

• GAP (Bermuda) Limited

  Shares: 7,366,818.00 · Class: 5.0%

• General Atlantic Cooperatief, L.P.

  Shares: 7,366,818.00 · Class: 5.0%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.