SCHEDULE 13G

Inspire Medical Systems Inc

Common Stock · CUSIP: 457730109

Event date: 2025-11-06

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Deerfield Mgmt, L.P.

  Shares: 1,476,303.00 · Class: 5.08%

• Deerfield Management Company, L.P.

  Shares: 1,476,303.00 · Class: 5.08%

• Deerfield Partners, L.P.

  Shares: 1,476,303.00 · Class: 5.08%

• James E. Flynn

  Shares: 1,476,303.00 · Class: 5.08%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.