SCHEDULE 13G

Lycia Therapeutics, Inc.

Common Stock, $0.0001 par value per share · CUSIP: 55081P100

Event date: 2026-10-23

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Venrock Healthcare Capital Partners III, L.P.

  Shares: 6,850,237.00 · Class: 11.9%

• VHCP Co-Investment Holdings III, LLC

  Shares: 6,850,237.00 · Class: 11.9%

• Venrock Healthcare Capital Partners EG, L.P.

  Shares: 6,850,237.00 · Class: 11.9%

• VHCP Management III, LLC

  Shares: 6,850,237.00 · Class: 11.9%

• VHCP Management EG, LLC

  Shares: 6,850,237.00 · Class: 11.9%

• Venrock Healthcare Capital Partners XP, L.P.

  Shares: 6,850,237.00 · Class: 11.9%

• VHCP Management XP, LLC

  Shares: 6,850,237.00 · Class: 11.9%

• Bong Y. Koh

  Shares: 6,850,237.00 · Class: 11.9%

• Nimish Shah

  Shares: 6,850,237.00 · Class: 11.9%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.