SCHEDULE 13G

LAKEFRONT BIOTHERAPEUTICS NV

Ordinary shares, no par value · CUSIP: 36315X101

Event date: 2025-10-27

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• TANG CAPITAL MANAGEMENT, LLC

  Shares: 5,559,674.00 · Class: 8.4%

• KEVIN TANG

  Shares: 5,559,674.00 · Class: 8.4%

• TANG CAPITAL PARTNERS, LP

  Shares: 3,313,189.00 · Class: 5.0%

• TANG CAPITAL PARTNERS INTERNATIONAL, LP

  Shares: 2,246,485.00 · Class: 3.4%

• TANG CAPITAL PARTNERS III, INC

  Shares: 0.00 · Class: 0.0%

• TANG CAPITAL PARTNERS IV, INC

  Shares: 0.00 · Class: 0.0%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.