SCHEDULE 13G

Rezolute Inc

Common Stock · CUSIP: 76200L309

Event date: 2025-12-12

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Opaleye Management Inc.

  Shares: 4,912,900.00 · Class: 5.30%

• Opaleye, L.P.

  Shares: 4,785,000.00 · Class: 5.16%

• James Silverman

  Shares: 4,912,900.00 · Class: 5.30%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.