SCHEDULE 13G/A

SYROS PHARMACEUTICALS, INC.

Common Stock, $0.001 par value per share · CUSIP: 87184Q107

Event date: 2024-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Invus Public Equities, L.P.

  Shares: 1,063,829 · Class: 3.8%

• Invus Public Equities Advisors, LLC

  Shares: 1,063,829 · Class: 3.8%

• Invus Global Management, LLC

  Shares: 1,063,829 · Class: 3.8%

• Siren, L.L.C.

  Shares: 1,063,829 · Class: 3.8%

• Avicenna Life Sci Master Fund LP

  Shares: 0 · Class: 0%

• Avicenna Life Sci Master GP LLC

  Shares: 0 · Class: 0%

• Ulys, L.L.C.

  Shares: 0 · Class: 0%

• Raymond Debbane

  Shares: 1,063,829 · Class: 3.8%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.