SCHEDULE 13G/A

Maze Therapeutics Inc

Common Stock, $0.001 par value per share · CUSIP: 578784100

Event date: 2025-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Third Rock Ventures IV, L.P.

  Shares: 4,473,958 · Class: 9.3%

• Third Rock Ventures GP IV, L.P.

  Shares: 4,473,958 · Class: 9.3%

• TRV GP IV, LLC

  Shares: 4,473,958 · Class: 9.3%

• Third Rock Ventures V, L.P.

  Shares: 950,800 · Class: 2.0%

• Third Rock Ventures GP V, L.P.

  Shares: 950,800 · Class: 2.0%

• TRV GP V, LLC

  Shares: 950,800 · Class: 2.0%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.