SCHEDULE 13D

ITEOS THERAPEUTICS INC

Common Stock, par value $0.001 per share · CUSIP: 46565G104

Event date: 2025-06-11

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• TANG CAPITAL MANAGEMENT, LLCReported CIK 0001232621

  Shares: 3,826,692.00 · Class: 9.99%

• KEVIN TANGReported CIK 0001178579

  Shares: 3,826,692.00 · Class: 9.99%

• TANG CAPITAL PARTNERS, LPReported CIK 0001191935

  Shares: 2,618,219.00 · Class: 6.84%

• TANG CAPITAL PARTNERS INTERNATIONAL, LPReported CIK 0002064011

  Shares: 1,208,473.00 · Class: 3.15%

• TANG CAPITAL PARTNERS III, INC

  Shares: 0.00 · Class: 0%

• TANG CAPITAL PARTNERS IV, INC

  Shares: 0.00 · Class: 0%

• CONCENTRA BIOSCIENCES, LLCReported CIK 0001970065

  Shares: 0.00 · Class: 0%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.