SCHEDULE 13G/A

Jade Biosciences Inc

Common Stock, $0.0001 par value per share · CUSIP: 008064206

Event date: 2025-06-30

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Frazier Life Sciences Public Fund, L.P.

  Shares: 1,340,703.00 · Class: 4.2%

• FHMLSP, L.P.

  Shares: 1,340,703.00 · Class: 4.2%

• FHMLSP, L.L.C.

  Shares: 1,340,703.00 · Class: 4.2%

• Frazier Life Sciences Public Overage Fund, L.P.

  Shares: 395,508.00 · Class: 1.2%

• FHMLSP Overage, L.P.

  Shares: 395,508.00 · Class: 1.2%

• FHMLSP Overage, L.L.C.

  Shares: 395,508.00 · Class: 1.2%

• Frazier Life Sciences X, L.P.

  Shares: 11,897.00 · Class: 0.0%

• FHMLS X, L.P.

  Shares: 11,897.00 · Class: 0.0%

• FHMLS X, L.L.C.

  Shares: 11,897.00 · Class: 0.0%

• Frazier Life Sciences XI, L.P.

  Shares: 24,008.00 · Class: 0.1%

• FHMLS XI, L.P.

  Shares: 24,008.00 · Class: 0.1%

• FHMLS XI, L.L.C.

  Shares: 24,008.00 · Class: 0.1%

• James N. Topper

  Shares: 11,897.00 · Class: 0.0%

• Patrick J. Heron

  Shares: 11,897.00 · Class: 0.0%

• Albert Cha

  Shares: 0.00 · Class: 0.0%

• James Brush

  Shares: 0.00 · Class: 0.0%

• Daniel Estes

  Shares: 0.00 · Class: 0.0%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.