SCHEDULE 13G/A

Lexeo Therapeutics Inc

Common Stock, $0.0001 par value per share · CUSIP: 52886X107

Event date: 2025-12-31

Reporting persons may disclose overlapping interests. Their amounts are shown individually and are not added into a filing total.

Filing-level shares

Unavailable

Percent of class

Unavailable

• Frazier Life Sciences Public Fund, L.P.

  Shares: 3,698,271.00 · Class: 5.1%

• FHMLSP, L.P.

  Shares: 3,698,271.00 · Class: 5.1%

• FHMLSP, L.L.C.

  Shares: 3,698,271.00 · Class: 5.1%

• Frazier Life Sciences X, L.P.

  Shares: 87,424.00 · Class: 0.1%

• FHMLS X, L.P.

  Shares: 87,424.00 · Class: 0.1%

• FHMLS X, L.L.C.

  Shares: 87,424.00 · Class: 0.1%

• Frazier Life Sciences XI, L.P.

  Shares: 232,784.00 · Class: 0.3%

• FHMLS XI, L.P.

  Shares: 232,784.00 · Class: 0.3%

• FHMLS XI, L.L.C.

  Shares: 232,784.00 · Class: 0.3%

• Frazier Life Sciences XII, L.P.

  Shares: 406,246.00 · Class: 0.6%

• FHMLS XII, L.P.

  Shares: 406,246.00 · Class: 0.6%

• FHMLS XII, L.L.C.

  Shares: 406,246.00 · Class: 0.6%

• James N. Topper

  Shares: 87,424.00 · Class: 0.1%

• Patrick J. Heron

  Shares: 87,424.00 · Class: 0.1%

Amounts are as disclosed in this filing. Schedule type alone does not establish investment intent.